Donald K Hamlin Selected Research

procaine isothiocyanate (PRIT)

12/2020	Therapy of Myeloid Leukemia using Novel Bispecific Fusion Proteins Targeting CD45 and 90Y-DOTA.
1/2018	CD38-bispecific antibody pretargeted radioimmunotherapy for multiple myeloma and other B-cell malignancies.
11/2016	Comparative Analysis of Bispecific Antibody and Streptavidin-Targeted Radioimmunotherapy for B-cell Cancers.
2/2014	A preclinical model of CD38-pretargeted radioimmunotherapy for plasma cell malignancies.
12/2011	Pretargeted radioimmunotherapy using genetically engineered antibody-streptavidin fusion proteins for treatment of non-hodgkin lymphoma.
7/2011	Anti-CD45 pretargeted radioimmunotherapy using bismuth-213: high rates of complete remission and long-term survival in a mouse myeloid leukemia xenograft model.
8/2009	Pretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates.
1/2009	Pretargeted radioimmunotherapy using anti-CD45 monoclonal antibodies to deliver radiation to murine hematolymphoid tissues and human myeloid leukemia.
2/2008	Eradication of disseminated leukemia in a syngeneic murine leukemia model using pretargeted anti-CD45 radioimmunotherapy.
6/2007	Comparative biodistributions of pretargeted radioimmunoconjugates targeting CD20, CD22, and DR molecules on human B-cell lymphomas.

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Donald K Hamlin Research Topics

Disease

22	Neoplasms (Cancer) 01/2022 - 05/2002
10	Lymphoma (Lymphomas) 01/2017 - 06/2007
7	Leukemia 01/2022 - 02/2008
6	B-Cell Lymphoma (Lymphoma, B Cell) 01/2017 - 06/2007
5	Hematologic Neoplasms (Hematological Malignancy) 01/2018 - 01/2005
5	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2017 - 06/2007
3	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2019
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2020 - 07/2011
3	Myeloid Leukemia (Leukemia, Myelocytic) 12/2020 - 01/2009
3	Multiple Myeloma 10/2019 - 02/2014
2	Ascites 11/2015 - 07/2002
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2022
1	Prostatic Neoplasms (Prostate Cancer) 01/2021
1	Blood-Borne Infections 11/2019
1	Hepatoblastoma 01/2019
1	Infertility (Sterility) 01/2018
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2016
1	Residual Neoplasm 03/2015
1	Plasmacytoma 02/2014

Drug/Important Bio-Agent (IBA)

11	Radioisotopes (Radionuclides)IBA 01/2022 - 05/2002
10	procaine isothiocyanate (PRIT)IBA 12/2020 - 06/2007
9	StreptavidinIBA 11/2016 - 05/2002
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2007
8	Biotin (Vitamin H)FDA Link 01/2018 - 05/2004
6	Monoclonal AntibodiesIBA 03/2015 - 09/2007
5	AntigensIBA 01/2022 - 06/2007
5	Astatine-211IBA 01/2021 - 06/2011
4	Indicators and Reagents (Reagents)IBA 06/2011 - 05/2004
3	DOTA-biotin (90Y-DOTA-biotin)IBA 12/2020 - 05/2009
3	AntibodiesIBA 01/2018 - 06/2007
3	HLA-DR Antigens (HLA-DR)IBA 05/2009 - 06/2007
3	Immunoconjugates (Immunoconjugate)IBA 09/2007 - 06/2007
2	alpha-Fetoproteins (alpha-Fetoprotein)IBA 12/2021 - 01/2019
2	GlypicansIBA 12/2021 - 01/2019
2	GalactosamineIBA 07/2010 - 06/2007
2	AcetylgalactosamineIBA 05/2009 - 09/2007
2	Surface Antigens (Surface Antigen)IBA 05/2009 - 06/2007
2	AcidsIBA 09/2007 - 06/2007
1	Fetal Proteins (Fetoprotein)IBA 01/2022
1	AstatineIBA 01/2022
1	human FOLH1 proteinIBA 01/2021
1	Glutamic Acid (Glutamate)FDA Link 01/2021
1	Lysine (L-Lysine)FDA Link 01/2021
1	Urea (Carbamide)FDA LinkGeneric 01/2021
1	LuciferasesIBA 01/2019
1	PyrogensIBA 01/2018
1	venetoclaxIBA 01/2017
1	Cesium-137IBA 01/2017
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2016
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2016
1	fludarabineIBA 01/2016
1	EnzymesIBA 11/2015
1	ADP-ribosyl Cyclase 1IBA 02/2014
1	BismuthIBA 07/2011
1	Single-Chain AntibodiesIBA 07/2010
1	Leukocyte Common Antigens (CD45 Antigen)IBA 01/2009
1	Neoplasm Antigens (Tumor Antigens)IBA 06/2007
1	Transaminases (Aminotransferases)IBA 07/2002

Therapy/Procedure

18	Radioimmunotherapy 01/2022 - 01/2005
12	Therapeutics 01/2022 - 05/2002
4	Cell Transplantation 01/2018 - 01/2005
3	Radiotherapy 01/2017 - 09/2007
3	Drug Therapy (Chemotherapy) 05/2013 - 09/2007
1	Aftercare (After-Treatment) 01/2022
1	Precision Medicine 12/2021
1	Injections 12/2020
1	Euthanasia (Mercy Killing) 12/2020
1	Hematopoietic Stem Cell Transplantation 05/2013
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 05/2013
1	Stem Cell Transplantation 09/2007
1	Chemoradiotherapy 09/2007